B2B marketing is most effective when it meets prospects where they are: across multiple channels with a personalized approach. Account-Based Marketing (ABM) is a prime example – 97% of marketers report higher ROI from ABM than other strategies. More broadly, multi-channel campaigns can drive nearly 5× higher ROI compared to single-channel efforts. However, executing truly integrated multi-channel campaigns – where each target segment or account gets tailored content across email, ads, landing pages, and social media – can be extremely resource-intensive.
This is where AI-powered tools come in. The latest AI marketing platforms help teams scale personalized outreach and content creation across channels, automating what used to be manual work. In 2025, advanced generative AI and automation mean highly tailored content and coordinated campaigns can be executed at scale like never before.
In this guide, we’ll compare the top AI tools for multi-channel B2B marketing campaigns. You’ll learn which platforms excel at multi-channel execution, personalization at scale, content generation and repurposing, campaign workflow automation, and enterprise usability – and why Tofu stands out as the ultimate choice for marketers looking to boost results across channels.
Best Overall – Tofu: Combines enterprise-scale personalization with multi-channel campaign automation. Tofu offers an all-in-one platform to create and execute hyper-personalized campaigns across email, web, ads, social media, and more, making it uniquely suited for multi-channel marketing at scale.
Best for Web Personalization – Mutiny: Ideal for teams focused on 1:1 website experiences. Mutiny automatically generates personalized landing pages (microsites) for each target account, which is great if your campaign strategy centers on web content. However, it limits itself to website experiences and doesn’t cover other channels.
Best Budget Tool – ChatGPT: If you’re on a tight budget, ChatGPT (the general-purpose AI chatbot) can help craft personalized messages and content ideas for your campaigns. It’s free (or low-cost for the Plus version), but keep in mind: ChatGPT has no built-in marketing workflows or integrations, so using it for multi-channel marketing at scale can become a manual, cumbersome process.
When evaluating AI tools for multi-channel B2B marketing, prioritize capabilities that will make your campaigns more personalized, automated, and effective. Key features and criteria include:
Personalization at Scale: The platform should automatically generate highly tailored content and experiences for each target account or segment. Look for AI that can incorporate account-specific or persona-specific details (e.g. industry, company facts, pain points) into emails, landing pages, ads, and social posts. The best tools (like Tofu) enable hyper-personalization for hundreds or even thousands of audiences without extra effort. By contrast, some point solutions can personalize one channel (like just the website) but struggle to scale across many accounts or touchpoints.
Multi-Channel Orchestration: Effective B2B campaigns are multi-channel by design. Your AI tool should support a range of channels – email, website content/microsites, digital ads, social media, direct mail, etc. – and coordinate them in a unified campaign. This ensures your personalized messaging reaches prospects wherever they engage. Tools that only focus on one channel (for example, Mutiny on websites only) may leave critical gaps in your outreach and customer journey.
Campaign Automation & Integrations: Automating the workflow of a campaign is crucial for efficiency. The ideal tool will not just create content, but also trigger and distribute it through your existing marketing stack. Look for features like playbooks or recipes that can automatically send emails, update ad audiences, or spin up personalized pages when an account reaches a certain stage or responds to an offer. Integration with your CRM and marketing automation platforms (e.g. Salesforce, HubSpot, Marketo) is key – your AI platform should plug into your pipeline so that personalization and campaign execution happen with minimal manual effort.
AI Content Quality & Repurposing: Multi-channel campaigns require a lot of tailored content, so ensure the AI’s writing quality and creativity meet your standards. The best tools have “custom AI brains” or brand-trained models to produce on-brand, accurate copy every time. Also consider whether the tool can repurpose content across formats – for example, turning a blog post into a personalized email series, or a webinar transcript into ad copy. This saves time by leveraging existing assets. Simpler AI writers might generate quick copy but often produce more generic content and lack the ability to reuse or adapt content for different channels.
Scalability & Enterprise Readiness: Finally, consider if the platform can support your team’s size, security, and workflow requirements. Enterprise-ready tools like Tofu offer features for large teams (user management, single sign-on, roles/permissions) and can handle campaigns with thousands of accounts or contacts. They also come with customer success support (onboarding, training) to help you ramp up quickly. Newer or niche tools might have a narrow focus and lack some enterprise features (for example, UserLed is an emerging ABM tool praised for ease of use but still developing deeper enterprise workflow capabilities). If data security and reliability are concerns, opt for a proven platform trusted by industry leaders.
We reviewed the leading AI platforms that B2B marketers are using for multi-channel personalized campaigns in 2025:
Tofu – An all-in-one AI marketing platform that combines content generation and multi-channel campaign orchestration in a single, enterprise-ready tool.
Mutiny – Specialized AI personalization software that creates 1:1 microsites and web experiences for target accounts. Great for personalized landing pages, but focuses mainly on the website channel.
UserLed – An AI-driven ABM tool to launch personalized campaigns faster. Emphasizes multi-channel 1:1 engagement (across ads, landing pages, email) and real-time sales signals, though it’s a newer solution with a narrower ABM-only focus.
Jasper – A popular AI writing assistant known for fast content creation. Comes with a rich template library for marketing copy and supports natural language commands, but it’s primarily a content generator (with limited depth in strategy or workflow integration for campaigns).
Copy.ai – An AI content generation platform geared toward go-to-market teams. It offers templates and some automated workflows for sales emails, social posts, and other marketing content. However, while it’s user-friendly for writing tasks, output quality can vary and it has relatively limited integrations into marketing systems.
ChatGPT – OpenAI’s general-purpose AI chatbot that many marketers use for idea brainstorming and copy drafting. It can generate personalized text if given the right prompts, but it isn’t built for marketing workflows – there’s no direct integration to your CRM or email tools, meaning everything from prompting to publishing content must be handled manually.
With those in mind, let’s dive into the top tools and see how they compare for the multi-channel campaign use case.
Tofu is the best overall AI marketing tool for multi-channel campaigns because it’s designed as a unified platform covering the entire campaign lifecycle – from content ideation and personalization to multi-channel distribution and analytics. Tofu brings together capabilities that would normally require several point solutions, enabling marketing teams to plan, create, and execute personalized campaigns all in one place. Crucially, it handles both the creative side (AI content generation) and the execution side (campaign orchestration). This means you can go from initial insight to a fully launched, multi-channel campaign in a fraction of the time it used to take (Tofu users report accelerating campaign execution by up to 8×).
Key Features:
Best For: Medium-to-large B2B marketing teams that want a single platform to run end-to-end multi-channel campaigns. If you need to personalize content for many targets and deliver it across multiple channels (and you value speed and deep integration), Tofu is an ideal choice. It’s especially powerful for organizations running extensive ABM or segmented campaigns – Tofu can handle large target lists (500+ accounts or thousands of individuals per campaign on higher-tier plans) while maintaining quality and consistency. That said, even lean teams benefit: Tofu helps a small team achieve what would normally require an army of content creators and campaign managers. By replacing the need for several separate tools (for example, Tofu can replace a web personalization tool, multiple copywriting tools, and certain email automation tasks), it delivers quick ROI. In short, Tofu is best for organizations that are serious about personalized multi-channel marketing and want the speed, scale, and sophistication of an all-in-one AI solution.
If your strategy is heavily focused on the website and landing page experience, Mutiny is a top choice. Mutiny is an AI-powered personalization platform that excels at creating 1:1 microsites and dynamically personalized web pages for each of your target accounts or segments. It’s a favorite for marketers who want to give VIP prospects a customized experience when they click through an ad or email – for example, a prospect arrives and sees a landing page greeting their company by name and showing relevant case studies. Mutiny’s strength is making this web personalization fast and scalable (with no coding required).
Key Features:
Best For: Marketing teams that prioritize web personalization as a core tactic, especially those running ABM or outbound programs that drive prospects to landing pages. Mutiny is often used by small-to-midsize teams who want a quick win in making their campaigns feel bespoke without a huge lift – you can create customized pages for dozens of accounts relatively easily. It’s an excellent choice if your goal is to wow target accounts with tailored web experiences. Just keep in mind that Mutiny’s focus is web; it doesn’t natively generate content for other channels like email or ads, so you’d pair it with other tools for a true multi-channel campaign. In other words, Mutiny shines for web personalization, but you’ll need additional solutions to cover outreach in email, social, etc., since it’s not an all-in-one campaign platform.
UserLed is a newer entrant focused on helping teams run multi-channel 1:1 campaigns more easily. The premise of UserLed is to bring some of the personalization magic of Mutiny beyond the website – into ads, emails, and sales outreach – while providing a friendly, fast interface. It positions itself as an “ABM accelerator” for companies that want true 1:1 personalization across every touchpoint but may not have a large team or big budget. If you’re looking to experiment with AI-powered ABM across channels without the complexity of an enterprise platform, UserLed is an intriguing option.
Key Features:
Best For: Small to mid-sized B2B teams that want to dip their toes into multi-channel ABM with AI assistance. UserLed is a strong fit for companies that find enterprise tools like Tofu powerful but possibly more than they currently need. For example, a startup or growth-stage company running ABM on a few dozen high-priority accounts might choose UserLed to get quick results without a heavy investment. It’s also well-suited for organizations that value breadth over depth – meaning you want coverage of many channels from one tool, even if each individual feature isn’t the absolute best in class. Do keep in mind that UserLed is a newer platform, and some advanced features (like very complex multi-step workflow automation or deep content repurposing capabilities) are not as mature. Its focus is specifically 1:1 marketing, so it won’t replace a general AI writing tool for broader needs. Also, if you require rigorous enterprise controls or extensive integrations beyond the basics (CRM, LinkedIn, etc.), you might find limitations. Overall, UserLed is best for nimble teams seeking an easy, all-in-one booster for personalized campaigns across email, web, and ads without a steep learning curve.
Jasper is widely known as one of the leading AI copywriting tools on the market. While it’s not a multi-channel campaign platform per se, many marketing teams use Jasper to generate content for their campaigns – such as drafting personalized emails or creating social media posts and ad copy for target segments. Jasper’s strength lies in its ease of use and content quality. It’s an excellent choice if your primary challenge is producing enough personalized content and copy, and you plan to handle the campaign orchestration separately (e.g. in your marketing automation or CRM system).
Key Features:
Best For: Marketing teams and content creators who need to generate a lot of personalized copy quickly. Jasper shines for content creation at scale – so if your multi-channel strategy involves writing individualized messages or adapting content for each segment, Jasper can save hours. For example, a single marketer can use Jasper to draft 50 personalized email variants in the time it would normally take to write just a few. It’s also a relatively budget-friendly option compared to full campaign platforms; you can use Jasper alongside your existing tools (CRM, email marketing software, etc.) as a content supplement. However, remember that Jasper is just a content tool – it doesn’t know who your specific targets are or when to send content. There’s no built-in campaign scheduling or integration with your contact lists. You’ll need to copy the content Jasper creates over into your marketing systems manually. Additionally, Jasper may occasionally produce output that sounds a bit generic or “AI-written” if you don’t fine-tune your prompts. Users note that it’s great for first drafts, but you should plan to review and polish the text for the best results. All in all, choose Jasper if content bandwidth is your main bottleneck and you want a proven AI writer to augment your team.
Copy.ai is another AI writing platform, similar in many ways to Jasper, but it has started to position itself as a broader “GTM (Go-To-Market) AI platform” with features geared toward both marketing and sales workflows. For multi-channel campaign purposes, Copy.ai can help generate personalized content for both outbound sales sequences and inbound marketing assets. It’s known for a very user-friendly interface and a variety of templates that cover not just writing, but even some minor workflow automation for content creation. If your campaign approach is tightly aligned with sales – say your SDRs/BDRs are heavily involved in 1:1 outreach – Copy.ai might serve as a handy AI assistant for that joint effort.
Key Features:
Best For: Sales-oriented ABM teams and those looking for a budget-friendly content solution. Copy.ai is a fit if your ABM program or campaign is a joint effort between marketing and a sales development team, and you need to produce a lot of personalized sales outreach (emails, LinkedIn messages) alongside marketing content. It’s also one of the more affordable options – there’s a free tier for basic usage, and paid plans tend to be cheaper than enterprise-grade platforms. That makes it attractive for startups or small businesses running personalized campaigns with limited budget. Use Copy.ai if you want an easy-to-use AI writer that’s a bit more focused on outbound sales content than Jasper. On the flip side, if you need deep strategy features or robust automation, Copy.ai might fall short – users note that the quality of output can be hit-or-miss at times, and that it doesn’t plug into marketing systems as smoothly as one would like for true campaign automation. It’s best deployed as a copy assistant to generate first drafts and creative ideas, which your team can then refine and send through your normal marketing and sales channels.
ChatGPT (the AI chatbot from OpenAI) isn’t a marketing tool per se, but it’s impossible to ignore in this landscape – many scrappy marketers use ChatGPT as a zero- or low-cost way to generate personalized content and brainstorm campaign ideas. If you have no budget or just want to experiment with AI-driven personalization before investing in a platform, ChatGPT can be a helpful starting point. It’s essentially a very powerful AI writing assistant that you can prompt with whatever you need. The catch is that you’ll be doing a lot of the work yourself to use it for multi-channel marketing, and it has no awareness of your specific audience or accounts unless you feed it information each time.
Key Features:
Best For: Individual marketers or very small teams who need an ultra-budget solution, or anyone who wants to experiment with AI-driven personalization without commitment. ChatGPT is best if you have more time than money – you can certainly achieve quality personalized content with it, but you must invest effort to provide context and handle the execution logistics. It can also be a complementary tool: even if you have a platform like Tofu, you might still use ChatGPT on the side for quick brainstorming or an outside-the-box idea. Just be cautious: since ChatGPT isn’t specialized for marketing, it may sometimes produce content that is off-tone or too generic, and it won’t remember specifics about your targets between sessions. Always double-check any facts it outputs (the AI can occasionally invent details if not carefully guided). In summary, ChatGPT is an amazingly powerful general AI that can support multi-channel marketing tasks in a pinch, but for streamlined and scalable operations, dedicated tools will serve you far better.
In a landscape full of AI tools, Tofu stands out as the most comprehensive solution for multi-channel B2B marketing campaigns. The key difference is that Tofu was built from the ground up to be an all-in-one orchestration and content generation platform, whereas most other options are point solutions tackling one part of the puzzle. This unified approach gives Tofu several unique advantages:
Ultimately, Tofu excels because it was purpose-built to solve the exact challenges of personalized, multi-channel marketing. It wasn’t adapted from a generic AI tool; it was envisioned as the orchestration layer for modern, AI-driven B2B teams. That focus shows in the details – from how the AI maintains each brand’s voice, to the way the campaign dashboard links every personalized asset to engagement and pipeline metrics. If you’re aiming to deliver highly personalized experiences across email, ads, web, and social – without sacrificing scale and efficiency – Tofu provides a unique combination of capabilities that others simply can’t match in one package.
In the age of AI, orchestrating personalized campaigns across channels is no longer out of reach for teams of any size – if you have the right tool. We’ve covered a range of AI marketing tools in this comparison, each with their strengths, but Tofu clearly emerges as the top choice for executing multi-channel B2B campaigns at scale. With Tofu, you get the best of all worlds: content generation, personalization, campaign automation, and integration, all in one platform. It’s enterprise-ready for those who need it, yet agile enough for smaller teams looking to punch above their weight in marketing.
If your goal is to create meaningful, tailor-made experiences for your prospects across email, web, ads, and social – and to drive higher ROI from your efforts – investing in a platform like Tofu can be a game-changer. Why settle for piecemeal solutions or manual workarounds when a single AI-driven platform can elevate your entire go-to-market strategy?
Interested in seeing Tofu in action? Book a demo today and discover firsthand why it’s the best AI tool for orchestrating personalized multi-channel campaigns. Experience how quickly you can launch your next campaign – and leave your competition behind with outreach that scales in both volume and relevance.
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"I take a broad view of ABM: if you're targeting a specific set of accounts and tailoring engagement based on what you know about them, you're doing it. But most teams are stuck in the old loop: Sales hands Marketing a list, Marketing runs ads, and any response is treated as intent."
"ABM has always been just good marketing. It starts with clarity on your ICP and ends with driving revenue. But the way we get from A to B has changed dramatically."
"ABM either dies or thrives on Sales-Marketing alignment; there's no in-between. When Marketing runs plays on specific accounts or contacts and Sales isn't doing complementary outreach, the whole thing falls short."
"In our research at 6sense, few marketers view ABM as critical to hitting revenue goals this year. But that's not because ABM doesn't work; it's because most teams haven't implemented it well."
"To me, ABM isn't a campaign; it's a go-to-market operating model. It starts with cross-functional planning: mapping revenue targets, territories, and board priorities."
"With AI, we can personalize not just by account, but by segment, by buying group, and even by individual. That level of precision just wasn't possible a few years ago."
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6 interdependent stages that form a data-driven ABM engine: account selection, research, channel selection, content generation, orchestration, and optimization
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Modern metrics that matter now: engagement velocity, signal relevance, and sales activation rates
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